Tramadol is an opioid analgesic used for the treatment of moderate to severe pain. It affects the central nervous system by blocking pain signals sent to the brain and altering the perception of pain. Tramadol binds to opioid receptors in the brain and spinal cord, leading to a reduction in pain sensations. Additionally, it inhibits the reuptake of serotonin and norepinephrine, enhancing its analgesic effect.

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Tramadol acts by activating mu-opioid receptors, which alters the perception of pain in the central nervous system. Besides this, tramadol inhibits the reuptake of serotonin and norepinephrine, further contributing to its analgesic effect. This combined action makes tramadol effective for treating various types of pain, including chronic and acute pain.

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